Whose physical fitness declines most with ADT?

Anyone reading this blog knows that exercise if the single best intervention for treating both the more bothersome and more serious side effects of ADT. The authors here ask: “Whose fitness declines the most with ADT?” Their answer includes those men who were unfit at the beginning of the study. No surprise there.

One other thing they found was that upper body strength declined more with ADT than lower body strength. 


Gonzalez BD, Jim HS, Small BJ, Sutton SK, Fishman MN, Zachariah B, Heysek RV, Jacobsen PB. 2015. Changes in physical functioning and muscle strength in men receiving androgen deprivation therapy for prostate cancer: a controlled comparison. Support Care Cancer 24(5):2201-2207. www.ncbi.nlm.nih.gov/pubmed/26563183