How is the cardiovascular disease a risk for Asian Men on ADT?

Based on this literature review, Asian men are different than Caucasian men when it comes to their response to ADT. Chinese men in particular may be at an increased risk of cardiovascular events. Also, surgical castration appears to increase the risk of dangerous blood clots more than LHRH agonist drugs for Chinese men. This paper is rich and strong in exploring the underlying genetics that may account for racial differences in how men respond to ADT. 

 

Teoh JY, Ng CF. 2016. Cardiovascular risk after androgen deprivation therapy for prostate cancer: an Asian perspective. Int Urol Nephrol 48(9):1429-1435. www.ncbi.nlm.nih.gov/pubmed/27256399