Key sentence from the paper: “These findings support the theory that only men with a relevant indication should receive systemic ADT, to minimize thromboembolic side effects.”

Key sentence from the paper: “There is a lack of data on how nutritional adjustments might affect ADT-associated adverse effects and the few studies that have investigated the integration of either nutritional counseling or modified diet have done so in conjunction with another intervention, making it difficult to specifically assess the impact of dietary changes.”

Key sentence from the paper: “What is now needed are exercise interventions that apply sound aerobic resistance training principles in combination to prevent the development of cardiovascular disease in men undergoing ADT for the treatment of prostate cancer.”

Key sentence from the paper: “Modern dose-escalating RT is likely to make the overall survival benefit [of neoadjuvant ADT] even smaller or possibly completely eliminate the benefit from ADT.”

Key sentence from the paper: “[T]here was no elevated risk of dementia for [prostate cancer] patients who received ADT compared to [prostate cancer] patients who did not receive ADT.”

Key sentence from the paper: “Medical professionals should be aware that the medication used for ADT, when administered to patients, may…trigger…falls.”

Key sentence from the paper: “Patients who received ADT with salvage radiotherapy were significantly more likely to be clinically or biochemically progression free 5 years after treatment than those who had radiotherapy alone, and they did not experience additional late adverse events: 5 year [progression-free survival] was 80% for radiotherapy plus ADT group and 62% in the radiotherapy alone group.”

Key sentence from the paper: “Chinese men appeared to have increased cardiac risk after ADT [compared to Caucasian men] while this was not observed in Japanese men.”

Key sentence from the paper: “…ADT results in elevated total cholesterol, [low density lipoprotein], cholesterol, [body mass index], and waits circumference values, which are all strong risk factors for [cardiovascular disease].”

Key sentence from the paper: “… statins may reduce the risk of prostate cancer progression, possibly in interaction with ADT use.”