Key sentence from the paper: “Overall survival was significantly longer in the immediate androgen-deprivation therapy arm compared with the delayed therapy arm.”
Read MoreIs it loss of testosterone or estradiol that accounts for bone loss in men on ADT?
Key sentence from the paper: “[T]he skeletal consequences of hypogonadism in men are primarily due to estrogen deficiency.”
Read MoreWhat is cardio-oncology?
Key sentence from the paper: “The physician’s focus should be to optimize the cardiovascular and metabolic risk profile as much as feasible over the course of survivorship.”
Read MoreCan ADT achieved with transdermal estradiol prevent the bone loss seen with other drugs?
Key sentence from the paper: “Transdermal oestradiol as a single agent produces castration levels of testosterone while mitigating [bone mineral density loss].”
Read MoreDoes anemia account for the fatigue experienced by men on ADT?
Key sentence from the paper: “[A]DT or orchiectomy caused a mild 10% decline in hemoglobin and [red blood cell] counts in men with non-metastatic prostate cancer without anemia prior to receiving treatment… ADT correlated with a decline in mental fatigue surrogate score...”
Read MoreHow helpful is exercise for patients on ADT?
Key sentence from the paper: “Although the effects of exercise interventions on [quality of life] are apparent, it is unclear whether these improvements are attributable to increased interventionist contact, aerobic exercise, resistance exercise, or the combination of all three..”
Read MoreIs there an alternative to LHRH drugs for shrinking the prostate gland before brachytherapy?
Key sentence from the paper: “[A] combination of dutasteride+bicalutamide showed a favourable toxicity profile compared to LHRH agonists in regard to EPIC sexual summary, EPIC sexual function and EPIC sexual bother scores.”
Read MoreAre the hot flashes and night sweats experiences by men on ADT identical to those experienced by menopausal women?
Key sentence from the paper: “…The levels of concordance and relationships between [subjective and objective assessment of hot flashes and night sweats] in this sample of men were similar to those of women…during…menopause and following treatments for breast cancer.”
Read MoreDoes having prostate cancer increase the risk of breaking a bone?
Key sentence from the paper: “…All [men with prostate cancer] should be risk assessed [for bone health]… rather than singling out men with ADT as all men with prostate cancer have an increased risk of fracture.”
Read MoreIs soccer the solution to overcoming ADT side effects?
Key sentence from Uth et al (2014): “…football training improves clinically relevant ourcomes and thus may be considered as a recommendable alternative to traditional rehabilitation interventions.”
Key sentence from Bruun et al (2014): “…football, due to its cultural representation of masculine ideals, may be a potent and unique strategy for increasing recruitment and adherence to physical activity in prostate cancer patients.”
Key sentence from Uth et al (2015): “Compared to standard care, 32 weeks of football training improved [bone mineral density] at clinically important femoral sites and parameters of physical functioning in men undergoing ADT for [prostate cancer].”
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